YAF2 anticorps (Middle Region)
Aperçu rapide pour YAF2 anticorps (Middle Region) (ABIN2780047)
Antigène
Voir toutes YAF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- YAF2 Antibody - middle region
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Séquence
- GDLTVIITDF KEKAKSAPAS SAAGDQHSQG SCSSDSTERG VSRSSSPRGE
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Homologie
- Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 80%, Mouse: 100%, Rat: 80%
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Attributs du produit
- This is a rabbit polyclonal antibody against YAF2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of mouse YAF2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37341-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- YAF2 (YY1 Associated Factor 2 (YAF2))
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Autre désignation
- YAF2
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Sujet
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Background Information: Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.
Gene Name: YY1 associated factor 2
Alternative Symbols: 2810021M11Rik
Protein Name: YY1-associated factor 2
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Poids moléculaire
- 20kDa
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ID gène
- 67057
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NCBI Accession
- NP_077151
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UniProt
- Q99LW6
Antigène
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