YAF2 anticorps (Middle Region)

N° du produit ABIN2780047

Détail du produit anti-YAF2 anticorps

Antigène: YAF2 (YY1 Associated Factor 2 (YAF2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YAF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GDLTVIITDF KEKAKSAPAS SAAGDQHSQG SCSSDSTERG VSRSSSPRGE

Homologie: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 80%, Mouse: 100%, Rat: 80%

Attributs du produit: This is a rabbit polyclonal antibody against YAF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse YAF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 179 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur YAF2

Antigène: YAF2 (YY1 Associated Factor 2 (YAF2))

Autre désignation: YAF2 (YAF2 Produits)

Synonymes: anticorps MGC75686, anticorps YAF2, anticorps zgc:136577, anticorps si:ch211-155a11.5, anticorps 2810021M11Rik, anticorps YY1 associated factor 2, anticorps YY1-associated factor 2, anticorps yaf2, anticorps YAF2, anticorps LOC100221270, anticorps Yaf2

Sujet: Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.
Alias Symbols: 2810021M11Rik
Protein Interaction Partner: Map3k1, Kdm2b, Rnf2,
Protein Size: 179

Poids moléculaire: 20 kDa

ID gène: 67057

NCBI Accession: NM_024189, NP_077151

UniProt: Q99LW6