FXYD5 anticorps (N-Term)

N° du produit ABIN2780210

Il existe 1 publication pour ce produit. L’anticorps anti-FXYD5 Polyclonal Lapin est utilisé pour la détection de FXYD5 dans des échantillons de Humain, Souris et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour FXYD5 anticorps (N-Term) (ABIN2780210)

Antigène: FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

Reactivité: Humain, Souris, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FXYD5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FXYD5 anticorps

Épitope: N-Term

Fonction: FXYD5 Antibody - N-terminal region

Séquence: LQPTSPTPTW PADETPQPQT QTQQLEGTDG PLVTDPETHK STKAAHPTDD

Homologie: Human: 100%, Mouse: 100%, Yeast: 90%

Attributs du produit: This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37690-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FXYD5 (ABIN2780210)

Song, Li, Sun, Zhao: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." dans: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).

Détails sur FXYD5

Antigène: FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

Autre désignation: FXYD5

Sujet:

Background Information: FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.

Gene Name: FXYD domain containing ion transport regulator 5

Alternative Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241

Protein Name: FXYD domain-containing ion transport regulator 5

Poids moléculaire: 20kDa

ID gène: 53827

NCBI Accession: NP_659003

UniProt: Q96DB9