MED21 anticorps (Middle Region)

N° du produit ABIN2780233

Cet anticorps Lapin Polyclonal détecte spécifiquement MED21 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour MED21 anticorps (Middle Region) (ABIN2780233)

Antigène: MED21 (Mediator Complex Subunit 21 (MED21))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED21 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MED21 anticorps

Épitope: Middle Region

Séquence: DSLPSEESTA ALQAASLYKL EEENHEAATC LEDVVYRGDM LLEKIQSALA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MED21. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MED21

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 144 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED21

Antigène: MED21 (Mediator Complex Subunit 21 (MED21))

Autre désignation: MED21

Sujet: MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: MAGEB4, SSC5D, ZNF655, BLOC1S6, MED21, CDK8, MED19, MED26, UBC, HTT, FBXW7, MED11, MED8, MED28, MED29, MED18, MED4, MED16, MED6, MED13, MED12, MED24, MED17, MED14, MED22, MED1, ELAVL1, VAV2, SKP1, THRA, THRB, MED10, TP53, SREBF1, ZC3H13, ZSCAN1, PCBD2, TA
Protein Size: 144

Poids moléculaire: 15 kDa

ID gène: 9412

NCBI Accession: NM_004264, NP_004255

UniProt: Q13503

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha