ZNF265 anticorps (N-Term)
Aperçu rapide pour ZNF265 anticorps (N-Term) (ABIN2780239)
Antigène
Voir toutes ZNF265 (Zranb2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- ZNF265 Antibody - N-terminal region
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Séquence
- RCGREKTTEA KMMKAGGTEI GKTLAEKSRG LFSANDWQCK TCSNVNWARR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against ZNF265. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF265
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8116410
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections." dans: The Journal of biological chemistry, Vol. 291, Issue 8, pp. 4019-34, (2016) (PubMed).
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- ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))
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Autre désignation
- ZNF265
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Sujet
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Background Information: ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.
Gene Name: Zinc finger, RAN-binding domain containing 2
Alternative Symbols: ZIS, ZIS1, ZIS2, ZNF265
Protein Name: Zinc finger Ran-binding domain-containing protein 2
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Poids moléculaire
- 37kDa
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ID gène
- 9406
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NCBI Accession
- NP_976225
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UniProt
- Q5VV34
Antigène
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