SP110 anticorps (Middle Region)

N° du produit ABIN2780261

Cet anticorps anti-SP110 Polyclonal Lapin (ABIN2780261) détecte spécifiquement SP110 dans WB. L’anticorps est réactif avec des échantillons de Humain et Cheval.

Aperçu rapide pour SP110 anticorps (Middle Region) (ABIN2780261)

Antigène: SP110 (SP110 Nuclear Body Protein (SP110))

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SP110 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SP110 anticorps

Épitope: Middle Region

Fonction: SP110 Antibody - middle region

Séquence: LKAYCHPQSS FFTGIPFNIR DYGEPFQEAM WLDLVKERLI TEMYTVAWFV

Homologie: Horse: 75%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SP110. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SP110

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37795-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SP110

Antigène: SP110 (SP110 Nuclear Body Protein (SP110))

Autre désignation: SP110

Sujet:

Background Information: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Gene Name: SP110 nuclear body protein

Alternative Symbols: IPR1, VODI, IFI41, IFI75

Protein Name: Sp110 nuclear body protein

Poids moléculaire: 81kDa

ID gène: 3431

NCBI Accession: NP_536349

UniProt: Q9HB58