Elf4 anticorps (N-Term)
Aperçu rapide pour Elf4 anticorps (N-Term) (ABIN2780359)
Antigène
Voir toutes Elf4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- ELF4 Antibody - N-terminal region
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Séquence
- MAITLQPSDL IFEFASNGMD DDIHQLEDPS VFPAVIVEQV PYPDLLHLYS
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against ELF4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ELF4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38028-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Elf4 (E74 like ETS transcription factor 4 (Elf4))
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Autre désignation
- ELF4
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Sujet
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Background Information: ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
Gene Name: E74-like factor 4 (ets domain transcription factor)
Alternative Symbols: MEF, ELFR
Protein Name: ETS-related transcription factor Elf-4
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Poids moléculaire
- 71kDa
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ID gène
- 2000
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NCBI Accession
- NP_001412
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UniProt
- Q99607
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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