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HMGA1 anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-HMGA1 a été validé pour WB. Il convient pour détecter HMGA1 dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Chévre et Saccharomyces cerevisiae.
N° du produit ABIN2780401

Aperçu rapide pour HMGA1 anticorps (N-Term) (ABIN2780401)

Antigène

Voir toutes HMGA1 Anticorps
HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Reactivité

  • 55
  • 38
  • 23
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Chévre, Saccharomyces cerevisiae

Hôte

  • 57
  • 11
  • 2
  • 2
Lapin

Clonalité

  • 60
  • 12
Polyclonal

Conjugué

  • 39
  • 11
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HMGA1 est non-conjugé

Application

  • 63
  • 27
  • 16
  • 14
  • 13
  • 13
  • 13
  • 13
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP

    Homologie

    Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against HMGA1. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA1
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 96 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

    Autre désignation

    HMGA1

    Sujet

    This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
    Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
    Protein Interaction Partner: NCOR2, UBE2I, PPARG, UBC, UPF2, HTT, OLA1, DNAJC8, PSIP1, METAP2, SYNCRIP, CWC27, HNRNPDL, EIF2S2, PCBP2, PCBP1, PA2G4, NPM1, NCL, HSPA1A, HNRNPL, HNRNPD, HNRNPAB, HNRNPA1, HMGB3, HMGB2, HMGB1, GTF2F2, XRCC6, CSNK2A1, RCC1, CDK1, APEX1, ANXA2, ANXA1, SSB,
    Protein Size: 96

    Poids moléculaire

    11 kDa

    ID gène

    3159

    NCBI Accession

    NM_002131, NP_002122

    UniProt

    Q5T6U8

    Pathways

    Nuclear Hormone Receptor Binding, Autophagy
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