HMGA1 anticorps (N-Term)

N° du produit ABIN2780401

Détail du produit anti-HMGA1 anticorps

Antigène: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Chévre, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP

Homologie: Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against HMGA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 96 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HMGA1

Antigène: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Autre désignation: HMGA1 (HMGA1 Produits)

Synonymes: anticorps HMG-R, anticorps HMGA1A, anticorps HMGIY, anticorps Hmgi, anticorps Hmgiy, anticorps hmga1, anticorps hmgiy, anticorps wu:fb12b06, anticorps wu:fb18f11, anticorps wu:fc19f01, anticorps wu:fi38b05, anticorps zgc:85677, anticorps AL023995, anticorps Hmga1a, anticorps Hmga1b, anticorps Hmgy, anticorps HMG-I(Y), anticorps HMG-Y, anticorps HMGA1, anticorps zgc:153948, anticorps high mobility group AT-hook 1, anticorps high mobility group protein HMG-I/HMG-Y, anticorps high mobility group AT-hook 1a, anticorps high mobility group AT-hook 1b, anticorps HMGA1, anticorps Hmga1, anticorps TSC_c24220, anticorps hmga1a, anticorps LOC705105, anticorps hmga1b

Sujet: This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
Protein Interaction Partner: NCOR2, UBE2I, PPARG, UBC, UPF2, HTT, OLA1, DNAJC8, PSIP1, METAP2, SYNCRIP, CWC27, HNRNPDL, EIF2S2, PCBP2, PCBP1, PA2G4, NPM1, NCL, HSPA1A, HNRNPL, HNRNPD, HNRNPAB, HNRNPA1, HMGB3, HMGB2, HMGB1, GTF2F2, XRCC6, CSNK2A1, RCC1, CDK1, APEX1, ANXA2, ANXA1, SSB,
Protein Size: 96

Poids moléculaire: 11 kDa

ID gène: 3159

NCBI Accession: NM_002131, NP_002122

UniProt: Q5T6U8

Pathways: Nuclear Hormone Receptor Binding, Autophagy