IRF1 anticorps (N-Term)

N° du produit ABIN2780408

Cet anticorps anti-IRF1 est un anticorps Lapin Polyclonal détectant IRF1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Mouton, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour IRF1 anticorps (N-Term) (ABIN2780408)

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Mouton, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IRF1 anticorps

Épitope: N-Term

Séquence: MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against IRF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 325 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IRF1

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Autre désignation: IRF1

Sujet: IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression.
Alias Symbols: IRF-1, MAR
Protein Interaction Partner: SUMO2, SUMO3, IRF2, KAT2B, EP300, PRDM1, UBC, BIRC3, MDM2, HIST1H3A, CBL, HSP90AA1, HSPA1A, Tbk1, STUB1, SPI1, QARS, IRF8, CDKN1B, TRIM28, SET, SP2, IRF9, YBX1, NPM1, TRMT2A, HCFC1, SEC63, KEAP1, TRAF3, CREBBP, tat, SMARCA4, STAT1, HMGA1, RELA, NFKB1, KAT
Protein Size: 325

Poids moléculaire: 37 kDa

ID gène: 3659

NCBI Accession: NM_002198, NP_002189

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy