IRF1 anticorps (C-Term)

N° du produit ABIN2780409

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Mouton et Cheval.

Aperçu rapide pour IRF1 anticorps (C-Term) (ABIN2780409)

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Mouton, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IRF1 anticorps

Épitope: C-Term

Fonction: IRF1 Antibody - C-terminal region

Séquence: YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IRF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of IRF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38129-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IRF1

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Autre désignation: IRF1

Sujet:

Background Information: IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Gene Name: Interferon regulatory factor 1

Alternative Symbols: MAR, IRF-1

Protein Name: Interferon regulatory factor 1

Poids moléculaire: 36kDa

ID gène: 3659

NCBI Accession: NP_002189

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy