IRF4 anticorps (Middle Region)

N° du produit ABIN501643

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF4 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Chien, Cobaye et Cheval.Il a été cité dans 1 publication.

Aperçu rapide pour IRF4 anticorps (Middle Region) (ABIN501643)

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivité: Humain, Rat, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF4 anticorps

Épitope: Middle Region

Séquence: TAHVEPLLAR QLYYFAQQNS GHFLRGYDLP EHISNPEDYH RSIRHSSIQE

Homologie: Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against IRF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IRF4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 451 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IRF4 (ABIN501643)

Han, Kraft, Nan, Guo, Chen, Qureshi, Hankinson, Hu, Duffy, Zhao, Martin, Montgomery, Hayward, Thomas, Hoover, Chanock, Hunter: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." dans: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, (2008) (PubMed).

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF4

Sujet: IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
Alias Symbols: LSIRF, MUM1, NF-EM5
Protein Interaction Partner: UBC, STAT6, BCL6, TOP1, IRAK1, PRRC2B, YTHDC2, VPS35, PEG10, TLK2, CARM1, IKBKAP, ETV7, BATF, HOXB13, PROX1, HOXC11, FKBP4, SPIB, PRDM1, MYD88, TRAF2, NFATC2, SPI1,
Protein Size: 451

Poids moléculaire: 52 kDa

ID gène: 3662

NCBI Accession: NM_002460, NP_002451

UniProt: Q15306

Pathways: Chromatin Binding