RING1 anticorps (Middle Region)

N° du produit ABIN2780456

Cet anticorps Lapin Polyclonal détecte spécifiquement RING1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye et Cheval.

Aperçu rapide pour RING1 anticorps (Middle Region) (ABIN2780456)

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RING1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RING1 anticorps

Épitope: Middle Region

Séquence: SDTGGPDGCG GEGGGAGGGD GPEEPALPSL EGVSEKQYTI YIAPGGGAFT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RING1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RING1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 406 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RING1

Antigène: RING1 (Ring Finger Protein 1 (RING1))

Autre désignation: RING1

Sujet: RING1 can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain.This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RNF1, RING1A
Protein Interaction Partner: CBX8, RYBP, YAF2, BMI1, UBC, SNAI1, EED, RNF2, HECW2, CSNK2A2, YY1, FBXO38, CBX7, CBX6, FHL1, TP53, NOTCH1, APP, PCGF1, PCGF5, PCGF6, PCGF3, PCGF2, CBX2, PHC3, WDR5, CBX4, PHC2, PHC1, YY2, ZFP42, SMARCAD1, PIK3R3, TOP2A, TERF2, TERF1, USP11, USP7, CENPA,
Protein Size: 406

Poids moléculaire: 42 kDa

ID gène: 6015

NCBI Accession: NM_002931, NP_002922

UniProt: Q06587