TEAD4 anticorps (C-Term)

N° du produit ABIN2780491

Cet anticorps Lapin Polyclonal détecte spécifiquement TEAD4 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour TEAD4 anticorps (C-Term) (ABIN2780491)

Antigène: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TEAD4 anticorps

Épitope: C-Term

Fonction: TEAD4 Antibody - C-terminal region

Séquence: MMNSVLENFT ILQVVTNRDT QETLLCIAYV FEVSASEHGA QHHIYRLVKE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TEAD4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113597

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TEAD4 (ABIN2780491)

Ribas, Moncaut, Siligan, Taylor, Cross, Rigby, Carvajal: "Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments." dans: Developmental biology, Vol. 355, Issue 2, pp. 372-80, (2011) (PubMed).

Détails sur TEAD4

Antigène: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Autre désignation: TEAD4

Sujet:

Background Information: TEAD4 is a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. TEAD4 is encoded through the use of a non-AUG (TTG) translation initiation codon. This gene encodes a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. This member is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. The protein is encoded through the use of a non-AUG (TTG) translation initiation codon. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: TEA domain family member 4

Alternative Symbols: TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B

Protein Name: Transcriptional enhancer factor TEF-3

Poids moléculaire: 48kDa

ID gène: 7004

NCBI Accession: NP_003204

UniProt: Q96BK2

Pathways: Regulation of Lipid Metabolism by PPARalpha