SAP30 anticorps (N-Term)

N° du produit ABIN2780555

Cet anticorps Lapin Polyclonal détecte spécifiquement SAP30 dans WB. Il présente une réactivité envers Humain, Souris, Lapin, Boeuf (Vache), Chien, Rat et Cobaye.

Aperçu rapide pour SAP30 anticorps (N-Term) (ABIN2780555)

Antigène: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Reactivité: Humain, Souris, Lapin, Boeuf (Vache), Chien, Rat, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP30 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SAP30 anticorps

Épitope: N-Term

Séquence: MNGFTPDEMS RGGDAAAAVA AVVAAAAAAA SAGNGTGAGT GAEVPGAGAV

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SAP30. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SAP30

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 220 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SAP30

Antigène: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Autre désignation: SAP30

Sujet: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
Protein Interaction Partner: HDAC3, CUL4B, DDB1, HDAC1, SIN3A, UBC, HDAC2, BRMS1L, ING1, ARID4A, SAMSN1, ZNF395, UBASH3B, RBBP7, RBBP4, CHD4, ALL1, TAF6, SMARCA2, SAP25, RBP1, HIST2H2BE, PCBD1, ID3, SAP30BP, HIST2H4A, HBP1, HIST1H2AL, BRMS1, CIR1, HIST3H3, NCOR1, NCOR2, MXD1, YY1, HT
Protein Size: 220

Poids moléculaire: 23 kDa

ID gène: 8819

NCBI Accession: NM_003864, NP_003855

UniProt: O75446