EZH2 anticorps (N-Term)

N° du produit ABIN2780595

Cet anticorps Lapin Polyclonal détecte spécifiquement EZH2 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye et Cheval.

Aperçu rapide pour EZH2 anticorps (N-Term) (ABIN2780595)

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-EZH2 anticorps

Épitope: N-Term

Séquence: KGPVCWRKRV KSEYMRLRQL KRFRRADEVK SMFSSNRQKI LERTEILNQE

Specificité: From peptide immunogen, will recognize all 5 isoforms.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EZH2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 751 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EZH2

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: EZH2

Sujet: EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.
Alias Symbols: ENX1, EZH1, KMT6, WVS2, ENX-1, KMT6A
Protein Interaction Partner: FBXW11, CEP63, HOTAIR, EED, BRCA1, SUZ12, SNAI1, SRSF1, SDCBP, UPF1, RBBP7, RBBP4, RAP1GAP, PLEC, PKM, POTEE, DHX36, AEBP2, HIST4H4, KLC4, SERPINB12, PHF5A, FIP1L1, FBXL18, CPSF7, DDX3X, DBN1, SLC25A10, COPB1, CALML3, ATP5C1, ATP5B, ATP2A2, ARG1, AR, ANXA
Protein Size: 751

Poids moléculaire: 85 kDa

ID gène: 2146

NCBI Accession: NM_001203247, NP_004447

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation