FOXA1 anticorps (N-Term)

N° du produit ABIN2780597

Détail du produit anti-FOXA1 anticorps

Antigène: FOXA1 (Forkhead Box A1 (FOXA1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Porc, Poisson zèbre (Danio rerio), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LGTVKMEGHE TSDWNSYYAD TQEAYSSVPV SNMNSGLGSM NSMNTYMTMN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 85%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%, Rat: 93%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against FOXA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 472 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FOXA1 (ABIN2780597)

Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." dans: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

Détails sur FOXA1

Antigène: FOXA1 (Forkhead Box A1 (FOXA1))

Autre désignation: FOXA1 (FOXA1 Produits)

Synonymes: anticorps HNF3A, anticorps TCF3A, anticorps Hnf-3a, anticorps Hnf3a, anticorps Tcf-3a, anticorps Tcf3a, anticorps fkd7, anticorps forkhead-7, anticorps HNF3-alpha, anticorps HNF3alpha, anticorps fkh2, anticorps foxa1, anticorps hnf3a, anticorps tFoxA1, anticorps tcf3a, anticorps xfkh2, anticorps fkh, anticorps FOXA1, anticorps Ci-fkh, anticorps HNF-3a, anticorps forkhead box A1, anticorps forkhead box A1 S homeolog, anticorps forkhead homolog, anticorps forkhead box A1 L homeolog, anticorps FOXA1, anticorps Foxa1, anticorps foxa1, anticorps foxa1.S, anticorps fkh, anticorps foxa1.L

Sujet: FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HNF3A, MGC33105, TCF3A
Protein Interaction Partner: EED, SEZ6L2, AHR, ELAVL1, SUMO2, TLE1, HDAC7, HIST3H3, AR, ONECUT1, DSCAM, NRIP1, XBP1, TFF1,
Protein Size: 472

Poids moléculaire: 49 kDa

ID gène: 3169

NCBI Accession: NM_004496, NP_004487

UniProt: P55317

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis