ONECUT1 anticorps (Middle Region)

N° du produit ABIN2780599

Cité dans 2 publications. Cet anticorps anti-ONECUT1 Polyclonal Lapin (ABIN2780599) détecte spécifiquement ONECUT1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Porc, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour ONECUT1 anticorps (Middle Region) (ABIN2780599)

Antigène: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Porc, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ONECUT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ONECUT1 anticorps

Épitope: Middle Region

Fonction: ONECUT1 Antibody - middle region

Séquence: ITISQQLGLE LSTVSNFFMN ARRRSLDKWQ DEGSSNSGNS SSSSSTCTKA

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ONECUT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38481-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ONECUT1 (ABIN2780599)

Yuan, Wang, Hu, Tang, Shi, Guo, Song: "Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition." dans: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 31206-16, (2013) (PubMed).

Huang, Mei, Yu, Zhang, Han, Jiang, Zhou: "Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig." dans: Acta histochemica, Vol. 111, Issue 2, pp. 157-65, (2009) (PubMed).

Détails sur ONECUT1

Antigène: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Autre désignation: ONECUT1

Sujet:

Background Information: ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.

Gene Name: One cut homeobox 1

Alternative Symbols: HNF6, HNF-6, HNF6A

Protein Name: Hepatocyte nuclear factor 6

Poids moléculaire: 51kDa

ID gène: 3175

NCBI Accession: NP_004489

UniProt: Q9UBC0