NRF1 anticorps (C-Term)
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- Antigène Voir toutes NRF1 Anticorps
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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Épitope
- C-Term
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NRF1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- IVLSGETAAA VGALTGVQDA NGLFMADRAG RKWILTDKAT GLVQIPVSMY
- Homologie
- Human: 100%, Rat: 91%
- Attributs du produit
- This is a rabbit polyclonal antibody against NRF1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NRF1
- Top Product
- Discover our top product NRF1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 522 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
- Autre désignation
- NRF1 (NRF1 Produits)
- Synonymes
- anticorps ALPHA-PAL, anticorps C87038, anticorps D6Ertd415e, anticorps SC:BZ3C13.1, anticorps SC:bZ3C13.2, anticorps ube2h, anticorps Nfe2l1_retired, anticorps IBR/F, anticorps NRF1, anticorps alpha-pal, anticorps nrf-1, anticorps LOC100220087, anticorps nuclear respiratory factor 1, anticorps nuclear respiratory factor 1 S homeolog, anticorps NRF1, anticorps Nrf1, anticorps nrf1, anticorps nrf1.S
- Sujet
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NRF1 is a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth.This gene encodes a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized.
Alias Symbols: ALPHA-PAL, EWG
Protein Interaction Partner: POGZ, TRAF2, SP4, FHL2, DYNLL1, CSNK2B, CSNK2A1, UBC, HHV8GK18_gp81, CEBPB, PARP1, PPRC1, MAFF, PPARGC1A, Dynlt1b, CDK1, MRPL57, TFAM,
Protein Size: 522 - Poids moléculaire
- 56 kDa
- ID gène
- 4899
- NCBI Accession
- NM_005011, NP_005002
- UniProt
- Q96AN2
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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