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ETS2 anticorps (Middle Region)

ETS2 Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin, Mouton, Chévre, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2780665
  • Antigène Voir toutes ETS2 Anticorps
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 46
    • 9
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin, Mouton, Chévre, Poisson zèbre (Danio rerio)
    Hôte
    • 41
    • 6
    Lapin
    Clonalité
    • 44
    • 3
    Polyclonal
    Conjugué
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ETS2 est non-conjugé
    Application
    • 35
    • 22
    • 16
    • 15
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    DPDEVARRWG KRKNKPKMNY EKLSRGLRYY YDKNIIHKTS GKRYVYRFVC
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ETS2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human ETS2
    Top Product
    Discover our top product ETS2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 469 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    Autre désignation
    ETS2 (ETS2 Produits)
    Synonymes
    anticorps 0123/09, anticorps 0608/07, anticorps 0998/12, anticorps 3520, anticorps CG17077, anticorps CG8705, anticorps D-Ets-2, anticorps D-ets-2, anticorps DMPOINT1A, anticorps Dmel\\CG17077, anticorps E(E2F)3D, anticorps EK3-2, anticorps ETS2, anticorps EY3-1, anticorps Ets, anticorps Ets2, anticorps Ets58AB, anticorps Ets94F, anticorps PNT-P1, anticorps PNTP1, anticorps PNTP2, anticorps POINT, anticorps Pnt, anticorps Pnt-P1, anticorps PntP1, anticorps PntP2, anticorps Pointed-P1, anticorps ets94F, anticorps l(3)07825, anticorps l(3)j1B7, anticorps l(3)s118306, anticorps png, anticorps pnt-P1, anticorps pnt-P2, anticorps pntP2, anticorps pntegfr, anticorps pointed-RC, anticorps ptd, anticorps zgc:92106, anticorps wu:fe02h08, anticorps wu:fk74c05, anticorps AU022856, anticorps Ets-2, anticorps ETS2IT1, anticorps c-ets-2, anticorps pointed, anticorps v-ets avian erythroblastosis virus E26 oncogene homolog 2, anticorps E26 avian leukemia oncogene 2, 3' domain, anticorps ETS proto-oncogene 2, transcription factor, anticorps pnt, anticorps ets2, anticorps Ets2, anticorps ETS2
    Sujet
    ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ETS2IT1
    Protein Interaction Partner: UBC, RFWD2, TWIST1, POU5F1, TWIST2, ZFYVE9, SRA1, XPO1, TP53, SUMO2, EP300, CREBBP, NCOR1, NCOA3, SRC, ZMYND11, TDP2, STAT5B, CDK10, SMARCA4, JUN, ERG, ETS2, ETS1, NR3C1, GATA3, FOS, SPI1, BRCA1,
    Protein Size: 469
    Poids moléculaire
    53 kDa
    ID gène
    2114
    NCBI Accession
    NM_005239, NP_005230
    UniProt
    P15036
    Pathways
    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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