GSC2 anticorps (C-Term)

N° du produit ABIN2780669

Cet anticorps Lapin Polyclonal détecte spécifiquement GSC2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour GSC2 anticorps (C-Term) (ABIN2780669)

Antigène: GSC2 (Goosecoid Homeobox 2 (GSC2))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GSC2 anticorps

Épitope: C-Term

Fonction: GSCL Antibody - C-terminal region

Séquence: LEALFVQNQY PDVSTRERLA GRIRLREERV EVWFKNRRAK WRHQKRASAS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 85%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against GSCL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GSCL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101870

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GSC2

Antigène: GSC2 (Goosecoid Homeobox 2 (GSC2))

Autre désignation: GSCL

Sujet:

Background Information: Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.

Gene Name: Goosecoid homeobox 2

Alternative Symbols: GSCL

Protein Name: Homeobox protein goosecoid-2

Poids moléculaire: 22kDa

ID gène: 2928

NCBI Accession: NP_005306

UniProt: O15499