MEF2D anticorps (Middle Region)
Aperçu rapide pour MEF2D anticorps (Middle Region) (ABIN2780725)
Antigène
Voir toutes MEF2D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Séquence
- GDGLSSPAGG SYETGDRDDG RGDFGPTLGL LRPAPEPEAE GSAVKRMRLD
-
Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against MEF2D. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MEF2D
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 521 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- MEF2D (Myocyte Enhancer Factor 2D (MEF2D))
-
Autre désignation
- MEF2D
-
Sujet
-
MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.MEF2D plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.MEF2D plays a critical role in the regulation of neuronal apoptosis.
Alias Symbols: DKFZp686I1536
Protein Interaction Partner: SUMO1, CDK6, ASCL1, APP, SUMO2, UBC, CABIN1, MEF2A, HDAC1, HIRA, ASH2L, KMT2D, RBBP5, MEN1, PRKACA, SENP3, HDAC4, COPS5, CARM1, PRMT5, KAT2B, HDAC3, SNCA, MAPK14, HDAC5, EP300, MAPK7, CASP7, MEF2D, MEF2C, NFATC2, SP1, YWHAQ,
Protein Size: 521 -
Poids moléculaire
- 56 kDa
-
ID gène
- 4209
-
NCBI Accession
- NM_005920, NP_005911
-
UniProt
- Q14814
Antigène
-