HDAC6 anticorps (C-Term)

N° du produit ABIN2780739

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC6 dans WB, IHC et ChIP. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Porc, Cobaye, Boeuf (Vache) et Cheval.

Aperçu rapide pour HDAC6 anticorps (C-Term) (ABIN2780739)

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Porc, Cobaye, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-HDAC6 anticorps

Épitope: C-Term

Séquence: VCHHEASEHP LVLSCVDLST WCYVCQAYVH HEDLQDVKNA AHQNKFGEDM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Hdac6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1149 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: Hdac6

Sujet: Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Alias Symbols: Hd6, Hdac5, Sfc6, mHDA2
Protein Interaction Partner: Hdac11, Ubc, Hsp90ab1, Park2, TARDBP, Vcp, USP47, HDAC6, PLAA, GARS, Tuba1a, Rela, Nfkb1, Mapt,
Protein Size: 1149

Poids moléculaire: 126 kDa

ID gène: 15185

NCBI Accession: NM_010413, NP_034543

UniProt: Q9Z2V5

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling