NKX3-1 anticorps (Middle Region)

N° du produit ABIN2780751

Détail du produit anti-NKX3-1 anticorps

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB)

Séquence: FSHQKYLSAP ERAHLAKNLK LTETQVKIWF QNRRYKTKRK QLSSELGDLE

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against NKX3-1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 234 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3-1 (NKX3-1 Produits)

Synonymes: anticorps Xbagpipe, anticorps Xbap, anticorps bagpipe, anticorps koza, anticorps nkx3-1, anticorps nkx3.1, anticorps si:ch211-67o1.2, anticorps nkx3a, anticorps MGC53041, anticorps MGC97890, anticorps Bax, anticorps NKX3.1, anticorps NKX3A, anticorps Nkx-3.1, anticorps BAPX2, anticorps NKX3, anticorps NK3 homeobox 1 L homeolog, anticorps NK3 homeobox 1, anticorps NK-3 transcription factor, locus 1 (Drosophila), anticorps nkx3-1.L, anticorps NKX3-1, anticorps nkx3-1, anticorps Nkx3-1

Sujet: The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAPX2, NKX3, NKX3.1, NKX3A
Protein Interaction Partner: STRA13, CHPF, AEN, RABL6, TEX264, STMN3, LMCD1, SPDEF, CKAP4, HNRNPA0, CCT7, HMG20B, FEM1B, HSP90B1, TPT1, RPL37A, RARG, PTMS, PEBP1, ND4, MNAT1, MAN2B1, RPSA, TOP1, WDR77, TOPORS, KAT2B, SP5, SP4, SP3, SP2, SP1, HDAC1, HIPK2, SRF,
Protein Size: 234

Poids moléculaire: 26 kDa

ID gène: 4824

NCBI Accession: NM_006167, NP_006158

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus