PEG3 anticorps (C-Term)
Aperçu rapide pour PEG3 anticorps (C-Term) (ABIN2780754)
Antigène
Voir toutes PEG3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- FGECSGYIER ASTSTGGANQ ADEKYFKCDV CGQLFNDRLS LARHQNTHTG
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against PEG3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1588 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PEG3 (Paternally Expressed 3 (PEG3))
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Autre désignation
- PEG3
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Sujet
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PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: PEG3, ALB, USP7, TRAF2, SIAH2, SIAH1, BRCA1,
Protein Size: 1588 -
Poids moléculaire
- 181 kDa
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ID gène
- 5178
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NCBI Accession
- NM_006210, NP_006201
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UniProt
- Q9GZU2
Antigène
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