POLR2I anticorps (N-Term)
Aperçu rapide pour POLR2I anticorps (N-Term) (ABIN2780755)
Antigène
Voir toutes POLR2I AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- EPDGTYEPGF VGIRFCQECN NMLYPKEDKE NRILLYACRN CDYQQEADNS
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Homologie
- Cow: 100%, Dog: 100%, Goat: 83%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against POLR2I. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2I
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 125 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POLR2I (Polymerase (RNA) II (DNA Directed) Polypeptide I, 14.5kDa (POLR2I))
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Autre désignation
- POLR2I
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Sujet
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POLR2I is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2I has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RPB9, hRPB14.5
Protein Interaction Partner: ESR1, TCEB3, SRC, PSMB9, UBC, MED19, MED26, RECQL5, TBCD, BRCA1, CPSF6, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, DCUN1D1, CUL5, MYC, tat, WDR48, POLR2H, MED10, MED29,
Protein Size: 125 -
Poids moléculaire
- 14 kDa
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ID gène
- 5438
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NCBI Accession
- NM_006233, NP_006224
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UniProt
- P36954
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Pathways
- Regulatory RNA Pathways
Antigène
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