ZBTB33 anticorps (N-Term)

N° du produit ABIN2780808

Cet anticorps Lapin Polyclonal détecte spécifiquement ZBTB33 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye et Lapin.

Aperçu rapide pour ZBTB33 anticorps (N-Term) (ABIN2780808)

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB33 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZBTB33 anticorps

Épitope: N-Term

Séquence: MESRKLISAT DIQYSGSLLN SLNEQRGHGL FCDVTVIVED RKFRAHKNIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ZBTB33. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ZBTB33

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 672 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZBTB33

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Autre désignation: ZBTB33

Sujet: ZBTB33 is a transcriptional regulator with bimodal DNA-binding specificity. ZBTB33 binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. ZBTB33 recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway. It may also activate transcription of a subset of target genes by the recruitment of CTNND2.
Alias Symbols: ZNF348, ZNF-kaiso
Protein Interaction Partner: HUWE1, SUMO2, SUMO3, CBFA2T3, LMNA, UBC, TCF7L2, KPNA2, CTNND1, CTNNB1, CTCF, ELAVL1, CTNND2, WDR48, NCOR1, ZBTB33, HDAC3, WNT11, S100A4, MMP7,
Protein Size: 672

Poids moléculaire: 74 kDa

ID gène: 10009

NCBI Accession: NM_006777, NP_006768

UniProt: Q86T24