SUPT16H anticorps (Middle Region)

N° du produit ABIN2780836

Détail du produit anti-SUPT16H anticorps

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Lapin, Cheval, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT16H est non-conjugé

Application: Western Blotting (WB)

Séquence: EESDYSKESL GSEEESGKDW DELEEEARKA DRESRYEEEE EQSRSMSRKR

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SUPT16H. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SUPT16H

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1047 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUPT16H

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Autre désignation: SUPT16H (SUPT16H Produits)

Synonymes: anticorps CDC68, anticorps FACTP140, anticorps SPT16/CDC68, anticorps CG1828, anticorps DRE4/dSPT16, anticorps Dmel\\CG1828, anticorps SPT16, anticorps Spt16, anticorps dSPT16, anticorps dSpt16, anticorps dspt16, anticorps l(3)62Bg, anticorps l(3)dre4, anticorps spt16, anticorps Cdc68, anticorps Fact140, anticorps Supt16h, anticorps T12H20.3, anticorps T12H20_3, anticorps global transcription factor C, anticorps SSF1, anticorps DDBDRAFT_0204912, anticorps DDBDRAFT_0231753, anticorps DDB_0204912, anticorps DDB_0231753, anticorps DUF140, anticorps SPT16 homolog, facilitates chromatin remodeling subunit, anticorps FACT complex subunit spt16, anticorps FACT complex subunit SPT16, anticorps CG1828 gene product from transcript CG1828-RB, anticorps suppressor of Ty 16, anticorps global transcription factor C, anticorps chromatin-remodeling protein SPT16, anticorps FACT complex component Spt16, anticorps chromatin-remodeling protein, anticorps global regulator of transcription, anticorps FACT (FAcilitates Chromatin Transcription) complex subunit, putative, anticorps SPT16 homolog, facilitates chromatin remodeling subunit S homeolog, anticorps SUPT16H, anticorps AOR_1_1808194, anticorps CC1G_05155, anticorps dre4, anticorps Supt16, anticorps SPT16, anticorps spt16, anticorps CDC68, anticorps Supt16h, anticorps supt16h, anticorps supt16h.S

Sujet: Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H. Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is the protein encoded by this gene. Sequence Note: The sequence AF152961.1 is a chimeric mRNA clone. Only the SUPT16H region was propagated into this RefSeq record. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDC68, FACT, FACTP140, FLJ10857, FLJ14010, FLJ34357, SPT16/CDC68
Protein Interaction Partner: HIST1H2AB, UBC, SUMO2, ATRX, SUMO1, NEDD8, RNF20, PAF1, EED, RNF2, BMI1, rev, FTH1, QRICH1, SRPK2, ICAM1, CD81, IGSF8, PNKP, VCP, FMNL1, SSRP1, ESR1, CENPA, LEO1, RBM25, PRPF6, NCSTN, RTF1, ACIN1, PSIP1, USP39, PRPF8, SF3A1, SAP18, CTR9, DDX21, PRPF3, PRP
Protein Size: 1047

Poids moléculaire: 120 kDa

ID gène: 11198

NCBI Accession: NM_007192, NP_009123

UniProt: Q9Y5B9

Pathways: Chromatin Binding