Interleukin enhancer-binding factor 3 (ILF3) (C-Term) anticorps

N° du produit ABIN2780868

L’anticorps anti-Interleukin enhancer-binding factor 3 Polyclonal Lapin est utilisé pour la détection de Interleukin enhancer-binding factor 3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin et Cheval. Il a été validé pour WB.

Aperçu rapide pour Interleukin enhancer-binding factor 3 (ILF3) (C-Term) anticorps (ABIN2780868)

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: C-Term

Fonction: ILF3 Antibody - C-terminal region

Séquence: SYQGKQGGYS QSNYNSPGSG QNYSGPPSSY QSSQGGYGRN ADHSMNYQYR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ILF3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ILF3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38969-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Autre désignation: ILF3

Sujet:

Background Information: ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.

Gene Name: Interleukin enhancer binding factor 3, 90 kDa

Alternative Symbols: CBTF, DRBF, MMP4, MPP4, NF90, NFAR, NF110, NF90a, NF90b, NF90c, NFAR2, TCP80, DRBP76, NF110b, NFAR-1, NFAR-2, NFAR90, TCP110, MPP4110, NF90ctv, NFAR110, MPHOSPH4, NF-AT-90

Protein Name: Interleukin enhancer-binding factor 3

Poids moléculaire: 95kDa

ID gène: 3609

NCBI Accession: NP_036350

UniProt: Q12906

Pathways: M Phase