MafF anticorps (N-Term)

N° du produit ABIN2780877

L’anticorps anti-MafF Polyclonal Lapin est utilisé pour la détection de MafF dans des échantillons de Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour MafF anticorps (N-Term) (ABIN2780877)

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MafF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MafF anticorps

Épitope: N-Term

Fonction: MAFF Antibody - N-terminal region

Séquence: SVRELNRHLR GLSAEEVTRL KQRRRTLKNR GYAASCRVKR VCQKEELQKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MAFF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114192

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MafF

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Autre désignation: MAFF

Sujet:

Background Information: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: V-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

Alternative Symbols: U-MAF, hMafF

Protein Name: Transcription factor MafF

Poids moléculaire: 18kDa

ID gène: 23764

NCBI Accession: NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction