CNOT7 anticorps (N-Term)

N° du produit ABIN2780900

L’anticorps Lapin Polyclonal anti-CNOT7 a été validé pour WB et IHC. Il convient pour détecter CNOT7 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cheval, Lapin, Cobaye, Chévre et Saccharomyces cerevisiae. Il y a 2+ publications disponibles.

Aperçu rapide pour CNOT7 anticorps (N-Term) (ABIN2780900)

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cheval, Lapin, Cobaye, Chévre, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CNOT7 anticorps

Épitope: N-Term

Séquence: TEFPGVVARP IGEFRSNADY QYQLLRCNVD LLKIIQLGLT FMNEQGEYPP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CNOT7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 262 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CNOT7 (ABIN2780900)

Maragozidis, Karangeli, Labrou, Dimoulou, Papaspyrou, Salataj, Pournaras, Matsouka, Gourgoulianis, Balatsos: "Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker." dans: Acta haematologica, Vol. 128, Issue 1, pp. 39-46, (2012) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur CNOT7

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Autre désignation: CNOT7

Sujet: CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: CAF1, hCAF-1
Protein Interaction Partner: FBXW11, TOB2, BTG2, FOXC2, UBC, BAG3, CNOT6, AGO2, AGO1, EPAS1, APP, ELAVL1, BTG1, Cnot3, HOXD4, IKBKG, BTG3, TOB1, CDK6, CDK4, CDK2, CDK1, PABPC1,
Protein Size: 262

Poids moléculaire: 30 kDa

ID gène: 29883

NCBI Accession: NM_013354, NP_037486

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization