NFYC anticorps (C-Term)

N° du produit ABIN2780913

L’anticorps anti-NFYC Polyclonal Lapin est utilisé pour la détection de NFYC dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Lapin et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour NFYC anticorps (C-Term) (ABIN2780913)

Antigène: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFYC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NFYC anticorps

Épitope: C-Term

Fonction: NFYC Antibody - C-terminal region

Séquence: GTQVVQGQIQ TLATNAQQIT QTEVQQGQQQ FSQFTDGQQL YQIQQVTMPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NFYC. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106886

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFYC

Antigène: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Autre désignation: NFYC

Sujet:

Targeted Subunit: gamma

Background Information: NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.

Gene Name: Nuclear transcription factor Y, gamma

Alternative Symbols: HSM, CBFC, HAP5, CBF-C, NF-YC, H1TF2A

Protein Name: Nuclear transcription factor Y subunit gamma

Poids moléculaire: 37kDa

ID gène: 4802

NCBI Accession: NP_055038

UniProt: Q13952

Pathways: Regulation of Lipid Metabolism by PPARalpha