SUZ12 anticorps (C-Term)

N° du produit ABIN2780973

L’anticorps Lapin Polyclonal anti-SUZ12 a été validé pour WB. Il convient pour détecter SUZ12 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval et Cobaye. Il y a 1 publication disponible.

Aperçu rapide pour SUZ12 anticorps (C-Term) (ABIN2780973)

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUZ12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SUZ12 anticorps

Épitope: C-Term

Séquence: ESASPANEEI TEEQNGTANG FSEINSKEKA LETDSVSGVS KQSKKQKL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SUZ12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SUZ12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 739 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SUZ12 (ABIN2780973)

De Cegli, Iacobacci, Flore, Gambardella, Mao, Cutillo, Lauria, Klose, Illingworth, Banfi, di Bernardo: "Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation." dans: Nucleic acids research, Vol. 41, Issue 2, pp. 711-26, (2013) (PubMed).

Détails sur SUZ12

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Autre désignation: SUZ12

Sujet: A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7,17)(p15,q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CHET9, JJAZ1, KIAA0160
Protein Interaction Partner: FBXW11, EZH2, BRCA1, CDK5RAP2, RBM22, LUC7L, NHP2, H2AFY2, C17orf85, NAT10, ATAD3A, HEATR1, PTCD3, CHCHD3, CDKAL1, DDX56, GDAP1, LUC7L3, SF3B6, LUC7L2, NOP58, LIMA1, CDC40, CRNKL1, HP1BP3, STOML2, TRA2A, RBM15B, REPIN1, PRPF19, AKAP8L, TBL2, DAZAP1, PHGDH
Protein Size: 739

Poids moléculaire: 83 kDa

ID gène: 23512

NCBI Accession: NM_015355, NP_056170

UniProt: Q15022