PRRX2 anticorps (N-Term)

N° du produit ABIN2781006

Cet anticorps Lapin Polyclonal détecte spécifiquement PRRX2 dans WB. Il présente une réactivité avec des échantillons de Souris, Humain, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour PRRX2 anticorps (N-Term) (ABIN2781006)

Antigène: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Reactivité: Souris, Humain, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRRX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRRX2 anticorps

Épitope: N-Term

Fonction: PRRX2 Antibody - N-terminal region

Séquence: RKNFSVSHLL DLEEVAAAGR LAARPGARAE AREGAAREPS GGSSGSEAAP

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 79%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PRRX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRRX2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39248-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PRRX2 (ABIN2781006)

Tokutomi, Araki, Kataoka, Yamamoto, Kim-Mitsuyama: "Oxidation of Prx2 and phosphorylation of GRP58 by angiotensin II in human coronary smooth muscle cells identified by 2D-DIGE analysis." dans: Biochemical and biophysical research communications, Vol. 364, Issue 4, pp. 822-30, (2007) (PubMed).

Détails sur PRRX2

Antigène: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Autre désignation: PRRX2

Sujet:

Background Information: PRRX2 is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.

Gene Name: Paired related homeobox 2

Alternative Symbols: PMX2, PRX2

Protein Name: Paired mesoderm homeobox protein 2

Poids moléculaire: 27kDa

ID gène: 51450

NCBI Accession: NP_057391

UniProt: Q99811