ERGIC2 anticorps (N-Term)
Aperçu rapide pour ERGIC2 anticorps (N-Term) (ABIN2781015)
Antigène
Voir toutes ERGIC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- ERGIC2 Antibody - N-terminal region
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Séquence
- MRRLNRKKTL SLVKELDAFP KVPESYVETS ASGGTVSLIA FTTMALLTIM
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against ERGIon Channel2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERGIC2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39265-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ERGIC2 (ERGIC and Golgi 2 (ERGIC2))
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Autre désignation
- ERGIC2
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Sujet
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Background Information: ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.
Gene Name: ERGIC and golgi 2
Alternative Symbols: PTX1, CDA14, Erv41, cd002
Protein Name: Endoplasmic reticulum-Golgi intermediate compartment protein 2
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Poids moléculaire
- 43kDa
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ID gène
- 51290
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NCBI Accession
- NP_057654
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UniProt
- Q96RQ1
Antigène
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