KLHL3 anticorps (Middle Region)

N° du produit ABIN2781024

Cet anticorps Lapin Polyclonal détecte spécifiquement KLHL3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Lapin, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour KLHL3 anticorps (Middle Region) (ABIN2781024)

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KLHL3 anticorps

Épitope: Middle Region

Fonction: KLHL3 Antibody - middle region

Séquence: LYVVGGDDGS CNLASVEYYN PVTDKWTLLP TNMSTGRSYA GVAVIHKSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KLHL3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39277-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur KLHL3

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Autre désignation: KLHL3

Sujet:

Background Information: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

Gene Name: Kelch-like 3 (Drosophila)

Alternative Symbols: PHA2D

Protein Name: Kelch-like protein 3

Poids moléculaire: 65kDa

ID gène: 26249

NCBI Accession: NP_059111

UniProt: Q9UH77