ZNF446 anticorps (C-Term)

N° du produit ABIN2781046

Cet anticorps Lapin Polyclonal détecte spécifiquement ZNF446 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Cobaye, Chien, Boeuf (Vache), Cheval et Lapin.

Aperçu rapide pour ZNF446 anticorps (C-Term) (ABIN2781046)

Antigène: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Reactivité: Humain, Rat, Souris, Cobaye, Chien, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF446 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZNF446 anticorps

Épitope: C-Term

Fonction: ZNF446 Antibody - C-terminal region

Séquence: SYPCEECGCS FSWKSQLVIH RKSHTGQRRH FCSDCGRAFD WKSQLVIHRK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF446

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39319-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZNF446

Antigène: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Autre désignation: ZNF446

Sujet:

Background Information: ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.

Gene Name: Zinc finger protein 446

Alternative Symbols: ZSCAN30, ZSCAN52, ZKSCAN20

Protein Name: Zinc finger protein 446

Poids moléculaire: 49kDa

ID gène: 55663

NCBI Accession: NP_060378

UniProt: Q9NWS9