HOXA5 anticorps (C-Term)
Aperçu rapide pour HOXA5 anticorps (C-Term) (ABIN2781081)
Antigène
Voir toutes HOXA5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Séquence
- FNRYLTRRRR IEIAHALCLS ERQIKIWFQN RRMKWKKDNK LKSMSMAAAG
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against HOXA5. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human HOXA5
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 270 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- HOXA5 (Homeobox A5 (HOXA5))
-
Autre désignation
- HOXA5
-
Sujet
-
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of the gene encoding HOXA5 may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HOX1, HOX1.3, HOX1C, MGC9376
Protein Interaction Partner: PRMT6, TWIST1, UBC, ELAVL1, SOX2, ZNF408, GTF2A1L, SMAD1, DDIT3, PBX1, MEIS1, FOXA2, CDX4, FOXO1,
Protein Size: 270 -
Poids moléculaire
- 30 kDa
-
ID gène
- 3202
-
NCBI Accession
- NM_019102, NP_061975
-
UniProt
- A2D5Y4
Antigène
-