REXO4 anticorps (N-Term)

N° du produit ABIN2781102

Cet anticorps anti-REXO4 est un anticorps Lapin Polyclonal détectant REXO4 dans WB. Adapté pour Humain et Rat.

Aperçu rapide pour REXO4 anticorps (N-Term) (ABIN2781102)

Antigène: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REXO4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-REXO4 anticorps

Épitope: N-Term

Séquence: MGKAKVPASK RAPSSPVAKP GPVKTLTRKK NKKKKRFWKS KAREVSKKPA

Homologie: Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human REXO4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 422 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur REXO4

Antigène: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Autre désignation: REXO4

Sujet: The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Alias Symbols: REX4, XPMC2, XPMC2H
Protein Interaction Partner: UBC, SIRT7, ESR2, ESR1,
Protein Size: 422

Poids moléculaire: 47 kDa

ID gène: 57109

NCBI Accession: NM_020385, NP_065118

UniProt: Q9GZR2