GATAD2B anticorps (N-Term)

N° du produit ABIN2781110

Cet anticorps anti-GATAD2B est un anticorps Lapin Polyclonal détectant GATAD2B dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour GATAD2B anticorps (N-Term) (ABIN2781110)

Antigène: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATAD2B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GATAD2B anticorps

Épitope: N-Term

Séquence: MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GATAD2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GATAD2B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 593 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GATAD2B

Antigène: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Autre désignation: GATAD2B

Sujet: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
Alias Symbols: P66beta, RP11-216N14.6
Protein Interaction Partner: USHBP1, CEP70, RPGRIP1, TEX11, MBD3, TRIM27, PRKAB2, GOLGA2, CALCOCO2, TRAF1, SUMO2, UBC, ZBTB1, SUZ12, EED, RNF2, HDAC2, HDAC1, SMAD2, MTA3, NOTCH1, MTA2, MTA1, NDUFA7, NDUFA2, SOX2, PARK7, tat, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, RBBP7, RBBP4, Fox
Protein Size: 593

Poids moléculaire: 65 kDa

ID gène: 57459

NCBI Accession: NM_020699, NP_065750

UniProt: Q8WXI9