AHRR anticorps (Middle Region)

N° du produit ABIN2781113

Cet anticorps Lapin Polyclonal détecte spécifiquement AHRR dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache) et Cobaye.

Aperçu rapide pour AHRR anticorps (Middle Region) (ABIN2781113)

Antigène: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AHRR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AHRR anticorps

Épitope: Middle Region

Séquence: LPQSEPPHQL CARGRGEQSC TCRAAEAAPV VKREPLDSPQ WATHSQGMVP

Homologie: Cow: 82%, Dog: 85%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Mouse: 91%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against AHRR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AHRR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 719 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AHRR

Antigène: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Autre désignation: AHRR

Sujet: Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor kappa-B.Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AHH, AHHR, KIAA1234, MGC167813, MGC176630, bHLHe77
Protein Interaction Partner: ANKRA2, HDAC5, HDAC4, ESR1, ARNT,
Protein Size: 719

Poids moléculaire: 78 kDa

ID gène: 57491

NCBI Accession: NM_020731, NP_065782

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha