GRHL3 anticorps (C-Term)

N° du produit ABIN2781145

Il existe 1 publication pour ce produit. L’anticorps anti-GRHL3 Polyclonal Lapin est utilisé pour la détection de GRHL3 dans des échantillons de Humain, Souris, Chien, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin et Porc. Il a été validé pour WB, IHC et ChIP.

Aperçu rapide pour GRHL3 anticorps (C-Term) (ABIN2781145)

Antigène: GRHL3 (Grainyhead-Like 3 (GRHL3))

Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRHL3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-GRHL3 anticorps

Épitope: C-Term

Fonction: GRHL3 Antibody - C-terminal region

Séquence: EEVFDALMLK TPDLKGLRNA ISEKYGFPEE NIYKVYKKCK RGILVNMDNN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GRHL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GRHL3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39489-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GRHL3 (ABIN2781145)

Darido, Georgy, Wilanowski, Dworkin, Auden, Zhao, Rank, Srivastava, Finlay, Papenfuss, Pandolfi, Pearson, Jane: "Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis." dans: Cancer cell, Vol. 20, Issue 5, pp. 635-48, (2011) (PubMed).

Détails sur GRHL3

Antigène: GRHL3 (Grainyhead-Like 3 (GRHL3))

Autre désignation: GRHL3

Sujet:

Background Information: GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.

Gene Name: Grainyhead-like 3 (Drosophila)

Alternative Symbols: SOM, VWS2, TFCP2L4

Protein Name: Grainyhead-like protein 3 homolog

Poids moléculaire: 57 kDa, 70 kDa

ID gène: 57822

NCBI Accession: NP_937817

UniProt: Q8TE85