HOXB8 anticorps (N-Term)

N° du produit ABIN2781203

L’anticorps anti-HOXB8 Polyclonal Lapin est utilisé pour la détection de HOXB8 dans des échantillons de Humain, Souris, Rat, Chien, Porc, Lapin, Boeuf (Vache), Cheval et Mouton. Il a été validé pour WB.

Aperçu rapide pour HOXB8 anticorps (N-Term) (ABIN2781203)

Antigène: HOXB8 (Homeobox B8 (HOXB8))

Reactivité: Humain, Souris, Rat, Chien, Porc, Lapin, Boeuf (Vache), Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXB8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HOXB8 anticorps

Épitope: N-Term

Fonction: HOXB8 Antibody - N-terminal region

Séquence: MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH

Homologie: Cow: 79%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against HOXB8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39583-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HOXB8

Antigène: HOXB8 (Homeobox B8 (HOXB8))

Autre désignation: HOXB8

Sujet:

Background Information: HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Gene Name: Homeobox B8

Alternative Symbols: HOX2, HOX2D, Hox-2.4

Protein Name: Homeobox protein Hox-B8

Poids moléculaire: 28kDa

ID gène: 3218

NCBI Accession: NP_076921

UniProt: P17481