CBLL1 anticorps (C-Term)
Aperçu rapide pour CBLL1 anticorps (C-Term) (ABIN2781231)
Antigène
Voir toutes CBLL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- CBLL1 Antibody - C-terminal region
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Séquence
- PFTQPGGMSP GIWPAPRGPP PPPRLQGPPS QTPLPGPHHP DQTRYRPYYQ
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096292
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." dans: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).
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- CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))
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Autre désignation
- CBLL1
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Sujet
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Background Information: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].
Gene Name: Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1
Alternative Symbols: HAKAI, RNF188
Protein Name: E3 ubiquitin-protein ligase Hakai
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Poids moléculaire
- 55kDa
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ID gène
- 79872
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NCBI Accession
- NP_079090
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UniProt
- Q75N03
Antigène
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