STEAP3 anticorps (C-Term)

N° du produit ABIN2781298

Cet anticorps Lapin Polyclonal détecte spécifiquement STEAP3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval et Lapin.

Aperçu rapide pour STEAP3 anticorps (C-Term) (ABIN2781298)

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STEAP3 anticorps

Épitope: C-Term

Fonction: STEAP3 Antibody - C-terminal region

Séquence: VALVLSTLHT LTYGWTRAFE ESRYKFYLPP TFTLTLLVPC VVILAKALFL

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human STEAP3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43515-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur STEAP3

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Autre désignation: STEAP3

Sujet:

Background Information: AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.

Gene Name: STEAP family member 3, metalloreductase

Alternative Symbols: STMP3, TSAP6, pH yde, AHMIO2, dudlin-2, dudulin-2

Protein Name: Metalloreductase STEAP3

Poids moléculaire: 56kDa

ID gène: 55240

NCBI Accession: NP_878919

UniProt: A8K6E3

Pathways: Transition Metal Ion Homeostasis