GOT2 anticorps (N-Term)

N° du produit ABIN2781299

Cité dans 2 publications. Cet anticorps anti-GOT2 Polyclonal Lapin (ABIN2781299) détecte spécifiquement GOT2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Lapin, Chien, Cobaye et Saccharomyces cerevisiae.

Aperçu rapide pour GOT2 anticorps (N-Term) (ABIN2781299)

Antigène: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GOT2 anticorps

Épitope: N-Term

Fonction: GOT2 Antibody - N-terminal region

Séquence: VEMGPPDPIL GVTEAFKRDT NSKKMNLGVG AYRDDNGKPY VLPSVRKAEA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GOT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43517-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GOT2 (ABIN2781299)

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Tsai, Hong, Liou, Liao: "Association study of GOT2 genetic polymorphisms and schizophrenia." dans: Psychiatric genetics, Vol. 17, Issue 5, pp. 314, (2007) (PubMed).

Détails sur GOT2

Antigène: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Autre désignation: GOT2

Sujet:

Background Information: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

Alternative Symbols: KAT4, DEE82, KATIV, KYAT4, mitAAT

Protein Name: Aspartate aminotransferase, mitochondrial

Poids moléculaire: 45kDa

ID gène: 2806

NCBI Accession: NP_002071

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process