GOT2 anticorps (N-Term)

N° du produit ABIN2781299

Détail du produit anti-GOT2 anticorps

Antigène: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOT2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VEMGPPDPIL GVTEAFKRDT NSKKMNLGVG AYRDDNGKPY VLPSVRKAEA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GOT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 430 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GOT2 (ABIN2781299)

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Tsai, Hong, Liou, Liao: "Association study of GOT2 genetic polymorphisms and schizophrenia." dans: Psychiatric genetics, Vol. 17, Issue 5, pp. 314, (2007) (PubMed).

Détails sur GOT2

Antigène: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Autre désignation: GOT2 (GOT2 Produits)

Synonymes: anticorps KAT4, anticorps KATIV, anticorps mitAAT, anticorps AI789014, anticorps Got-1, anticorps cAspAT, anticorps cCAT, anticorps AL022787, anticorps FABP-pm, anticorps Got-2, anticorps mAspAT, anticorps ASPATA, anticorps got2, anticorps zgc:66329, anticorps fj40h07, anticorps wu:fj40h07, anticorps zgc:56425, anticorps glutamic-oxaloacetic transaminase 2, anticorps glutamic-oxaloacetic transaminase 1, soluble, anticorps glutamatic-oxaloacetic transaminase 2, mitochondrial, anticorps glutamic-oxaloacetic transaminase 2a, mitochondrial, anticorps glutamic-oxaloacetic transaminase 2 L homeolog, anticorps Aspartate amino transferase activity, anticorps glutamic-oxaloacetic transaminase 2b, mitochondrial, anticorps GOT2, anticorps got2, anticorps Got1, anticorps Got2, anticorps got2a, anticorps got2.L, anticorps AST, anticorps got2b

Sujet: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ40994, kat4, kativ, mitaat, KAT4, KATIV, mitAAT
Protein Interaction Partner: FUS, UBC, NEDD8, MDM2, CDK2, CCL21, GLRX, GAPDH, APCS, AI837181, HDAC5, PSMD4, THOC7, ZDHHC6, GLUD1, HSPA8, PC, MDH2, CTNNBIP1, MPG,
Protein Size: 430

Poids moléculaire: 45 kDa

ID gène: 2806

NCBI Accession: NM_002080, NP_002071

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process