STEAP3 anticorps (N-Term)

N° du produit ABIN2781309

Cet anticorps Lapin Polyclonal détecte spécifiquement STEAP3 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin et Porc.

Aperçu rapide pour STEAP3 anticorps (N-Term) (ABIN2781309)

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STEAP3 anticorps

Épitope: N-Term

Séquence: LVGSGFKVVV GSRNPKRTAR LFPSAAQVTF QEEAVSSPEV IFVAVFREHY

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STEAP3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 488 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STEAP3

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Autre désignation: STEAP3

Sujet: AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
Protein Size: 488

Poids moléculaire: 54 kDa

ID gène: 55240

NCBI Accession: NM_001008410, NP_001008410

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis