CPB2 anticorps (Middle Region)

N° du produit ABIN2781326

Détail du produit anti-CPB2 anticorps

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RSKSKDHEEL SLVASEAVRA IEKTSKNTRY THGHGSETLY LAPGGGDDWI

Homologie: Dog: 86%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 83%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CPB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CPB2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 423 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CPB2

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Autre désignation: CPB2 (CPB2 Produits)

Synonymes: anticorps CPU, anticorps PCPB, anticorps TAFI, anticorps 1110032P04Rik, anticorps 4930405E17Rik, anticorps AI255929, anticorps CPR, anticorps Cpu, anticorps pCPB, anticorps zgc:112493, anticorps carboxypeptidase B2, anticorps carboxypeptidase B2 (plasma), anticorps CPB2, anticorps Cpb2, anticorps cpb2

Sujet: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.
Alias Symbols: CPU, PCPB, TAFI
Protein Interaction Partner: FN1, TINAG, UBC, PZP, F2, PLG, C5, A2M,
Protein Size: 423

Poids moléculaire: 36 kDa

ID gène: 1361

NCBI Accession: NM_001872, NP_001863

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis