CPB2 anticorps (Middle Region)

N° du produit ABIN2781326

Cet anticorps anti-CPB2 Polyclonal Lapin (ABIN2781326) détecte spécifiquement CPB2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour CPB2 anticorps (Middle Region) (ABIN2781326)

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CPB2 anticorps

Épitope: Middle Region

Fonction: CPB2 Antibody - middle region

Séquence: RSKSKDHEEL SLVASEAVRA IEKTSKNTRY THGHGSETLY LAPGGGDDWI

Homologie: Dog: 86%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 83%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CPB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CPB2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43570-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CPB2

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Autre désignation: CPB2

Sujet:

Background Information: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.

Gene Name: Carboxypeptidase B2 (plasma)

Alternative Symbols: CPU, PCPB, TAFI

Protein Name: Carboxypeptidase B2

Poids moléculaire: 36kDa

ID gène: 1361

NCBI Accession: NP_001863

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis