MTTP anticorps (N-Term)

N° du produit ABIN2781495

Il existe 3+ publications pour ce produit. L’anticorps anti-MTTP Polyclonal Lapin est utilisé pour la détection de MTTP dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour MTTP anticorps (N-Term) (ABIN2781495)

Antigène: MTTP (Microsomal Triglyceride Transfer Protein (MTTP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTTP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MTTP anticorps

Épitope: N-Term

Fonction: MTTP Antibody - N-terminal region

Séquence: MILLAVLFLC FISSYSASVK GHTTGLSLNN DRLYKLTYST EVLLDRGKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MTTP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MTTP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105385

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MTTP (ABIN2781495)

Lee, Bao, Ishikawa, Wang, Lim: "Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila." dans: PLoS genetics, Vol. 13, Issue 1, pp. e1006555, (2017) (PubMed).

Ward, Dail, Chambers: "In Vitro effect of DDE exposure on the regulation of lipid metabolism and secretion in McA-RH7777 hepatocytes: A potential role in dyslipidemia which may increase the risk of type 2 diabetes mellitus." dans: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 37, pp. 9-14, (2016) (PubMed).

Lundahl, Skoglund-Andersson, Caslake, Bedford, Stewart, Hamsten, Packard, Karpe: "Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles." dans: American journal of physiology. Endocrinology and metabolism, Vol. 290, Issue 4, pp. E739-45, (2006) (PubMed).

Détails sur MTTP

Antigène: MTTP (Microsomal Triglyceride Transfer Protein (MTTP))

Autre désignation: MTTP

Sujet:

Background Information: MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Gene Name: Microsomal triglyceride transfer protein

Alternative Symbols: ABL, MTP

Protein Name: Microsomal triglyceride transfer protein large subunit

Poids moléculaire: 99 kDa

ID gène: 4547

NCBI Accession: NP_000244

UniProt: P55157

Pathways: Transition Metal Ion Homeostasis