Butyrylcholinesterase anticorps (N-Term)

N° du produit ABIN2781762

Cet anticorps Lapin Polyclonal détecte spécifiquement Butyrylcholinesterase dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Mouton, Cobaye, Porc et Lapin.Il a été cité dans 1 publication.

Aperçu rapide pour Butyrylcholinesterase anticorps (N-Term) (ABIN2781762)

Antigène: Butyrylcholinesterase (BCHE)

Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Mouton, Cobaye, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Butyrylcholinesterase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Butyrylcholinesterase anticorps

Épitope: N-Term

Fonction: BCHE Antibody - N-terminal region

Séquence: SSLHVYDGKF LARVERVIVV SMNYRVGALG FLALPGNPEA PGNMGLFDQQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BCHE. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BCHE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095796

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Butyrylcholinesterase (ABIN2781762)

Mizukami, Akatsu, Abrahamson, Mi, Ikonomovic: "Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 2, pp. 135-45, (2016) (PubMed).

Détails sur Butyrylcholinesterase

Antigène: Butyrylcholinesterase (BCHE)

Autre désignation: BCHE

Sujet:

Background Information: Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Gene Name: Butyrylcholinesterase

Alternative Symbols: E1, CHE1, CHE2, BCHED

Protein Name: Cholinesterase

Poids moléculaire: 68kDa

ID gène: 590

NCBI Accession: NP_000046

UniProt: P06276

Pathways: Peptide Hormone Metabolism