SGCB anticorps (Middle Region)

N° du produit ABIN2781779

Détail du produit anti-SGCB anticorps

Antigène: SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGCB est non-conjugé

Application: Western Blotting (WB)

Séquence: FSTDYETHEF HLPSGVKSLN VQKASTERIT SNATSDLNIK VDGRAIVRGN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SGCB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SGCB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 318 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SGCB

Antigène: SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Autre désignation: SGCB (SGCB Produits)

Synonymes: anticorps A3b, anticorps LGMD2E, anticorps SGC, anticorps 43kDa, anticorps AI747103, anticorps AI844814, anticorps beta-SG, anticorps CG5657, anticorps DmSCG-beta, anticorps Dmel\\CG5657, anticorps dscgbeta, anticorps scg-beta, anticorps beta-sarcoglycan, anticorps fa03a05, anticorps wu:fa03a05, anticorps zgc:110833, anticorps sarcoglycan beta, anticorps sarcoglycan, beta (dystrophin-associated glycoprotein), anticorps Sarcoglycan beta, anticorps SarcoGlycaN, anticorps uncharacterized LOC5567384, anticorps beta-sarcoglycan, anticorps sarcoglycan, beta, anticorps sarcoglycan beta L homeolog, anticorps SGCB, anticorps Sgcb, anticorps Scgbeta, anticorps sgn-1, anticorps LOC5567384, anticorps CpipJ_CPIJ006944, anticorps sgcb.L, anticorps sgcb

Sujet: SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD, MIM 300377) and syntrophin (SNTA1, MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA, MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1235 BC020709.1 1-1235 1236-1833 U31116.1 1257-1854 1834-4229 AK094731.1 47-2442
Alias Symbols: A3b, LGMD2E, SGC
Protein Interaction Partner: UBC, SGCZ, SGCG, SGCD, SGCA,
Protein Size: 318

Poids moléculaire: 35 kDa

ID gène: 6443

NCBI Accession: NM_000232, NP_000223

UniProt: Q16585

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location